TRIFER FOL

Lactation Asthma Folic acid deficiency Immune deficiency Child under 15 years of age Inflammatory Pregnancy Infection Hepatic impairment Dialysis patient Patients previously treated with oral therapy Patient subject to autologous sampling High dose treated patient Late skin porphyria Subject at risk of phosphorous depletion Allergic field Extended treatment Repeated treatment.

Mechanism of action

Iron is an essential component of the body.

It is necessary for the formation of hemoglobin and the oxidation processes of living tissues.

Ferrous fumarate contains 33% iron metal.

Ferrous salts are generally poorly absorbed (10-20% of the ingested dose).

This absorption is increased when iron reserves are reduced.

Absorption occurs mainly at the level of the duodenum and the proximal part of the jejunum.

The iron hydroxide-saccharose complex in solution allows iron to be fed by the intravenous route.

The stable complex of ferric hydroxide and dextran is similar to the physiological form of iron: ferritin (ferric hydroxide complex and phosphate protein) In imaging, as non-stoichiometric magnetite particles silylated, iron is a contrast product for MRI.

• (increase) (Uncommon)
• Hypophosphataemia (Uncommon)
• Liver enzymes (increase) (Uncommon)
• Ferritine (increase) (Uncommon)
• ASAT (increase) (Uncommon)
• Gamma GT (increase) (Uncommon)
• LDH (increase) (Rare)
• Urticaria (Uncommon)
• Dermatitis (Uncommon)
• Pruritus (Uncommon)
• Skin exfoliation (Uncommon)
• Rash (Common)
• Hypersudation (Uncommon)
• Exanthema (Uncommon)
• Facial Erythema (Uncommon)
• Hyperhidrosis (Rare)
• Palor Skin colour impairment Abnormal colouration at the injection site
• Chest suppression (Common)
• Pain (Uncommon)
• Peripheral edema (Uncommon)
• Frisher (Uncommon)
• Chest pain (Uncommon)
• Fever (Uncommon)
• Pain in limbs (Uncommon)
• Asthenia (Uncommon)
• Fatigue (Uncommon)
• Burning sensation (Uncommon)
• Irflu pseudo-influenza syndrome (Rare)
• Edema Deaths Cold sweat Fishbane reaction Hematoma Hypersensitivity (Uncommon)
• Angioedema (Rare)
• Anaphylactic reaction (Rare)
• Anaphylactoid reaction (Rare)
• Oedema of Quincke Delayed hypersensitivity
• Immediate hypersensitivity Infection (Uncommon)
• Phlebitis at the injection site (Uncommon)
• Infusion site reaction (Common)
• Injection site reaction (Common)
• Hematoma at the injection site
• Discoloration at the injection site Swelling at the injection site Erythema at the injection site
• Thrombophlebitis at the injection site Extravasation at the injection site Injection site edema
• Pruritus at the injection site Irritation at the injection site Injection site bruising
• Infusion site pain Pain at injection site Burning sensation at the injection site
• Fetal Bradycardia Blurty vision (Uncommon)
• Vertigo (Uncommon)
• Dysgueusia (Common)
• Dysphony (Rare)
• Metallic taste Mental confusion Anxiety Congestive puff (Uncommon)
• Hypertension (Common)
• Hot flash (Uncommon)
• Tachycardia (Uncommon)
• Hypotension (Common)
• Phlebitis (Uncommon)
• Syncope (Rare)
• Malaise (Rare)
• Arrhythmia (Rare)
• Palpitation (Rare)
• Cardiovascular collapsus Bradycardia Kounis syndrome Thrombophlebitis Constipation (Uncommon)
• Vomiting (Uncommon)
• Dyspepsia (Uncommon)
• Nausea (Common)
• Abdominal pain (Uncommon)
• Diarrhoea (Uncommon)
• Joint pain (Uncommon)
• Joint swelling (Common)
• Sleeping (Uncommon)
• Musculoskeletal scarring (Uncommon)
• Muscle pain (Uncommon)
• Muscle spasm (Uncommon)
• Cramp (Rare)
• Bone pain (Rare)
• Arthritis (Rare)
• Loss of consciousness (Uncommon)
• Paraesthesia (Uncommon)
• Headache (Uncommon)
• Trembling (Uncommon)
• Hypoesthesia (Uncommon)
• Mental damage (Rare)
• Convulsions (Rare)
• Somnolence (Rare)
• Epilepsy (crisis)
• Alteration of consciousness
• Dyspnoea (Uncommon)
• Bronchospasm (Uncommon)
• Difficulty breathing Urine colour (change) (Rare).