FREEGAS

Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination.

It has a favourable safety profile as it is not systemically absorbed.

Simethicone has been in use since the 1940s 1 but was granted FDA approval in 1952.

Simethicone is indicated for the treatment of bloating, pressure, and cramps caused by gas.

Simethicone is also used as part of bowel preparation for colonoscopies.

Simethicone decreases the surface tension of gas bubbles in the gastrointestinal tract, facilitating their expulsion.

It has a short duration of action as it is generally given as needed, and a wide therapeutic index as it is not systemically absorbed.

Simethicone is a surfactant that decreases the surface tension of gas bubbles in the gastrointestinal tract, more easily allowing gas to exit the body.

Target Actions Organism U Coagulation factor X inhibitor Humans.

Simethicone is not systemically absorbed and so these data are not readily available.

Simethicone is not systemically absorbed and so it is not metabolised by the body.

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Data regarding overdoses with simethicone are rare due to the fact that it is not systemically absorbed. 2.

In the case of an overdose stop the drug and initiate symptomatic and supportive care.