OXADEX
CONTINENTAL PHARM
Identification
- Active ingredient (INN)
- OXACILLINE SODIQUE EXPRIME EN OXACILLINE
- Internal code
- 13 G 160
- Country of Origin
- Algeria
- Pharmaceutical form
- Capsule
- Prescription List
- Highly Regulated (List I)
- Packaging
- b/12
DAWA Clinical Workbench v2.0
Information may not be accurate. Always consult a physician, pharmacist, or specialist before acting on any data shown here.
Description
An antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Indications
Used in the treatment of resistant staphylococci infections.
Pharmacodynamics
Oxacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms.
The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins.
Oxacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria.
The bactericidal activity of
Oxacillin results from the inhibition of cell wall synthesis and is mediated through Oxacillin binding to penicillin binding proteins (PBPs).
Oxacillin is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.
Mechanism of Action
serine-type D-Ala-D-Ala carboxypeptidase (Streptococcus pneumoniae) Inhibitor Penicillin-binding protein 2a (Streptococcus pneumoniae (strain ATCC BAA-255 / R6)) Inhibitor Penicillin-binding protein 1A (Streptococcus pneumoniae (strain ATCC BAA-255 / R6)) Inhibitor + 6 more targets.
Route of Elimination
Sodium is rapidly excreted as unchanged drug in the urine by glomerular filtration and active tubular secretion.
Adverse Effects
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