VENACINE

Use helps to reduce difficulty in falling asleep.

Thromboembolic accident Lactation History of psychiatric illness Recent history of intestinal anastomosis Cancer Septic shock Cirhrosis Ulcerous colitis Diabetes Diverticulitis Child between 30 months and 15 years Epilepsy Stress Glaucoma Glaucoma, family history (de) Pregnancy Herpes eye Hypertension Hypothyroidism Bacterial infection Intramuscular injection Congestive heart failure Hepatic impairment Renal impairment Surreal impairment Exanthemous disease Psychiatric illness Severe myasthenia Cortisonic myopathy Infants under 30 months of age Newborn exposed in utero to the medicine Osteoporosis Brain malaria Dialysis patient High dose treated patient Phoechromocytoma Poliomyelitis Premature Presence of varicella or measles in patient's environment Psychosis Systemic scleroderma Multiple sclerosis Sports Elderly Subject at risk of heart Subject at risk of thromboembolic accident Subject at risk of seizure Subject at risk of psychiatric illness Subject at risk for tumour lysis syndrome Subject at risk of tuberculosis Subject with a positive reaction to tuberculin Subject from an anguillasis endemic area Cushing's syndrome Allergic field Extended treatment Renal transplantation Cranial trauma Neuromuscular disorder Tuberculosis, history Evolutionary tuberculosis Gastroduodenal ulcer, history (d) Evolving gastroduodenal ulcer Non-live or inactivated vaccines.

Mechanism of action

Physiological glucocorticoids ( cortisone and hydrocortisone) are essential metabolic hormones.

Synthetic corticosteroids, including dexamethasone, are used primarily for their anti-inflammatory effect.

At high doses, they decrease the immune response.

Their metabolic and sodium retention effect is less than that of hydrocortisone.

• Alkaline phosphates (increase)
• Leucocytosis Hyperuricaemia ASAT (increase)
• Lipidaemia (amendment)
• Hypokalaemia Hypercalcuria ALT (increase)
• Skin atrophy (Common)
• Acne (Common)
• Rash
• Skin Erythema Vergeture Skin striation Skin depigmentation Urticaria Hyperhidrosis
• Pruritus Pétechie Recovery delay (Common)
• Fatigue Peripheral edema Hypopituitarism
• Cushingoid syndrome Hirsutism Inhibition of hypothalamo-pituito-adrenal axis Menstrual irregularity
• Echymosis Hematoma Hepatitis Abnormal skin test Oedema of Quincke Hypersensitivity
• Anaphylactoid reaction Anaphylactic reaction Esophagus candidiasis Infection (Common)
• Opportunistic infection Peritonitis Injection site reaction Waterproof detention (Common)
• Negative nitrogen balance Insulin resistance Hypokalemic alkalosis Glucose tolerance
• Weight (increase)
• Metabolic acidosis Appetite increased Epidural lipomatosis Subcapsular cataract (Common)
• Papillary edema Glaucoma Chorioretinopathy Cataract Intraocular hypertension Blurty vision
• Eye infection (aggravation)
• Exophthalmia Cornea thinning Feeling dizzy Dysgueusia
• Insomnia (Common)
• Confusion-oniric state (Rare)
• Manic access (Rare)
• Cognitive disorder
• Mood disorder Irritability Drug addiction Suicidal ideation Behavioural disorder
• Schizophrenia (aggravation)
• Hallucination Depression Euphoria Mental confusion Emotional disorder
• Mania Psychosis Delicious Personality disorder Anxiety Hypertension (Common)
• Hypertrophic cardiomyopathy
• Arrhythmia Congestive puff Hypotension Myocardial closure Lung embolism Telangiectasia
• Malaise Thromboembolic accident Congestive heart failure Gastroduodenal ulcer (Common)
• Digestive perforation Abdominal distension Acute Pancreatitis Dyspepsia Vomiting
• Cystic pneumatosis of the intestine Hoquet Nausea Digestive haemorrhage Abdominal pain
• Diarrhoea Esophagus Ulcer Esophagitis Muscle weakness (Common)
• Growth retardation (Common)
• Cortisonic myopathy Osteonecrosis Osteoporosis Myopathy Pathological fracture Muscle atrophy
• Muscle pain Strand cut Aseptic osteonecrosis of femoral heads Joint pain Convulsions (Rare)
• Headache Amnesia Intracranial hypertension Weaning syndrome Renal scleroderma crisis.

Do not use in children under 12 years of age with any other product containing doxylamine unless you have time for a full night’s sleep Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis glaucoma trouble urinating due to an enlarged prostate gland Ask a doctor or pharmacist before use if you are taking sedatives or any other sleep-aid tranquilizers any other antihistamines any other drugs When using this product avoid alcoholic beverages do not drive a motor vehicle or operate machinery take only at bedtime Stop use and ask a doctor if sleeplessness persists continuously for more than two weeks.

Insomnia may be a symptom of serious underlying medical illness.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

In case of overdose, get medical help or contact a Poison Control Center right away.

Directions adults and children 12 years of age and over: take one tablet 30 minutes before going to bed; take once daily or as directed by a doctor children under 12 years of age: do not use.

Other information TAMPER EVIDENT

DO NOT USE IF OUTER PACKAGE IS OPENED OR BLISTER IS TORN OR BROKEN store at controlled room temperature 20°-25°C (68°-77°F) see end flap for expiration date and lot number.