INHASTA

Lactation QT space extension Halogenated hydrocarbon anesthesia Aneurysm Recent history of myocardial infarction Arrhythmia Severe asthma Obstructive Cardiomyopathy Severe Cardiopathies Diabetes Children under 5 years of age Epilepsy Asthma exacerbation Pregnancy Bronchial hypersecretion Hypertension Hyperthyroidism Hypoxia Bronchi infection Severe heart failure Coronary heart failure Myocardial Ischemia Cardiovascular disease Infants under 18 months of age Newborn exposed in utero to the medicine Patient with hand/lung synchronization difficulties High dose treated patient Phoechromocytoma Sports Subject at risk of QT space prolongation Subject at risk of hypokalaemia Tachyarrhythmia.

Mechanism of action

Salbutamol is a beta-adrenergic receptor agonist with much more selective action on beta-2 receptors.

In pneumonology, after inhalation, salbutamol exerts a stimulating action on beta-2 receptors of smooth bronchial muscle, thus ensuring rapid, significant bronchodilation in a few minutes, and persistent for 4-6 hours.

In gynaecology, at the usual therapeutic doses, salbutamol exerts a stimulating action on beta-2 receptors of uterine smooth fibres.

It reduces the amplitude, frequency and duration of uterine contractions.

• Plasma ketone bodies (increase) (Rare)
• LDH (increase) (Rare)
• Glycerolaemia (increase) (Rare)
• Hyperglycaemia (Rare)
• Hypokalaemia (Rare)
• Free fatty acids (increase) (Rare)
• Hyperlactataemia (Rare)
• Hyperinsulinism (Rare)
• Hypersudation (Common)
• Skin Erythema (Very rare)
• Urticaria (Very rare)
• Rash (Very rare)
• Pruritus (Very rare)
• Exanthema Local reaction (Common)
• Thrombocytopenia (Very rare)
• Angioedema (Very rare)
• Hypersensitivity (Very rare)
• Lactic acidosis (Rare)
• Vertigo (Common)
• Dysgueusia (Common)
• Oral irritation (Uncommon)
• Irritation of the throat (Uncommon)
• Feeling dizzy (Common)
• Hyposialia (Rare)
• Oral pain (Rare)
• Burning of the tongue Agitation (Common)
• Hallucination (Very rare)
• Insomnia (Very rare)
• Behavioural disorder (Very rare)
• Nervousness (Very rare)
• Sleep disorder (Very rare)
• Tachycardia (Common)
• Palpitation (Uncommon)
• Peripheral vasodilation (Rare)
• Tensile instability (Rare)
• Hypotension (Very rare)
• Arrhythmia (Rare)
• Cardiovascular collapsus (Very rare)
• Myocardial Ischemia (Very rare)
• Angor (Rare)
• Sinus tachycardia Blood pressure (increase)
• Blood pressure (decrease)
• Superventricular tachycardia Extrasystole Atrial fibrillation
• Hypertension Nausea (Common)
• Vomiting (Rare)
• Cramp (Uncommon)
• Muscle pain Headache (Common)
• Trembling (Common)
• Hyperactivity (Rare)
• Hand trembling Central nervous system stimulation
• Bronchospasm paradoxical (Rare)
• Cough (Rare)
• Bronchospasm Nephropathy (Very rare).