NUTRISON MULTIFIBRE

Uses for use as a lubricant to prevent further irritation to relieve dryness of the eye.

Lactation Cumulative doses

Child under 15 years of age Pregnancy Hypovolaemia Intraventricular injection Intrathecal injection Hepatic impairment Renal impairment Myasthenia Infant under 1 year of age Newborn exposed in utero to the medicine High dose treated patient Porphyry Nephrotoxic treatment in progress Extended treatment.

The prodrogue of the colistin, which is a polypeptic antibiotic of the polymyxin family, of the group of polymyxins E. The colistin is characterized by a rapid bactericidia which is accompanied by a weakly marked, if not non-existent, postantibiotic effect vis-à-vis the polypepticicic group of the polymyxin family, prolonged (particularly in vivo) vis-à-vis the Pseudomonas aeruginosa and Acinetobacter spp.

Its mechanism of action, not completely elucidated, is bound to a polycationic effect deorganizing the phosphate groups of the lipopolysaccharides of the membrane of the bacilli to Gram negative.

This interaction is responsible for an increase in the permeability of the merginary and a leakage of the intracellular content, causing the death of the bacterium.

This mechanism of action may be responsible for a synergy with other antibiotics, a pseudoactive organism, a known to be resistant, agente aPC, aspecta, a specicherobic acidic acidic acidic acidic acidic acidic acid.

• Blood creatinine (increase) (Very common)
• Creatinine clearance (decrease) (Very common)
• Uremia (increase) (Very common)
• Neutropenia Proteinuria Alkaline phosphates (increase)
• Transaminases (increase)
• Cylindrical disease Pruritus (Very common)
• Rash Urticaria
• Flushing Fever Numbness of the extremities Bartter's Pseudos syndrome Leucopenia
• Hypersensitivity Angioedema Pain at injection site Injection site reaction Blurty vision
• Vision disorder Vertigo Dizziness of the language Feeling dizzy Dysphony Mental confusion
• Psychosis Temporospatial disorientation Vasomotor instability Vasomotor reaction
• Pseudomembranous colitis Gastrointestinal discomfort Diarrhoea Muscle weakness (Very common)
• Headache (Very common)
• Peribuccal paraesthesia (Very common)
• Oral paresthesia (Very common)
• Facial paraesthesia (Very common)
• Neurotoxicity (Very common)
• Neuromuscular block
• Meningation Convulsions Coma Respiratory paralysis Neuropsychic disorder Speech Disorder
• Ataxia Paresthesia of the extremities Dyspnoea Apnea Renal impairment (Very common)
• Haematuria Acute tubular necrosis Oliguria.

Warnngs For external use only

Do not use ■ if this product changes color or becomes cloudy ■ if seal is broken or punctured When using this product ■ do not touch tip of container to any surface to avoid contamination ■ replace cap after each use Stop use and consult a physician if you experience any of the following ■ eye pain ■ changes in vision ■ irritation or redness for longer than 72 hours If pregnant or breast-feeding, ask a health professional before use.

Do not use if this product changes color or becomes cloudy if you are sensitive to any ingredient in this product When using this product do not touch the tip of container to any surface to avoid contamination replace cap after each use Stop use and consult a physician if you experience any of the following: eye pain changes in vision occur irritation or redness for longer than 72 hours Keep out of reach of children If swallowed, get medical help or contact a Poison Control Center right away If pregnant or breastfeeding ask a health professional before use.

Instill 1 or 2 drops in the affected eye(s) as needed.

If pregnant or breastfeeding ask a health professional before use.