LISINOX

Uses treats frequent heartburn (occurs 2 or more days a week) not intended for immediate relief of heartburn; this drug may take to 4 days for full effect.

Children under 12 years of age Helicobacter pylori infection Severe hepatic impairment Severe renal impairment Osteoporosis Elderly Subject at risk of osteoporosis Subject at risk of vitamin B12 deficiency Subject at risk of fracture Processing on request Extended treatment Gastric ulcer.

esomeprazole: Mechanism of action Esomeprazole is the S-isomer of omeprazole.

It decreases acid gastric secretion by a specifically targeted mechanism of action.

It is a proton pump inhibitor (PPI) specific to the parietal cell.

The two R and

S isomers of omeprazole have similar pharmacodynamic activity.

Esomeprazole is a weak base.

It is concentrated and converted into an active form in the acid environment of the secretory canalicles of parietal cells, where it inhibits the enzyme H + K + -ATPase (proton pump), basal acid secretion and stimulated acid secretion.

During antisecretory treatment, the concentration of gastrin in the serum increases in the acidic environment of the secretory canalicles of the parietal cells, where it inhibits the enzyme H + K + -ATPase (proton pump), basal acid secretion and stimulated acid secretion.

During the antisecretory treatment, the gastron cells are slightly reduced in the form of the gastron cells, the gastron cells are given a possible pathosis to the pathosis of the pathosis of the pathosis of the pathosis, which is observed in the.

• Liver enzymes (increase) (Uncommon)
• Hyponatremia (Rare)
• Hypomagnesaemia (Very rare)
• Hypocalcaemia Hypokalaemia Urticaria (Uncommon)
• Rash (Uncommon)
• Dermatitis (Uncommon)
• Pruritus (Uncommon)
• Toxic epidermal necrolysis (Very rare)
• Stevens-Johnson Syndrome (Very rare)
• Hypersudation (Rare)
• Polymorphic Erythema (Very rare)
• Photosensitivity (Rare)
• Alopecia (Rare)
• Peripheral edema (Uncommon)
• Fever Gynecomastia (Very rare)
• Agranulocytosis (Very rare)
• Thrombocytopenia (Rare)
• Leucopenia (Rare)
• Pancytopenia (Very rare)
• Ictery (Rare)
• Hepatic impairment (Very rare)
• Hepatitis (Rare)
• DRESS syndrome (Very rare)
• Hypersensitivity (Rare)
• Subacute erythematous cutaneous lupus Anaphylactic shock Anaphylactic reaction Angioedema
• Digestive candidiasis (Rare)
• Blurty vision (Rare)
• Vertigo (Uncommon)
• Oral dryness (Uncommon)
• Feeling dizzy (Uncommon)
• Stomatitis (Rare)
• Dysgueusia (Rare)
• Insomnia (Uncommon)
• Hallucination (Very rare)
• Aggressiveness (Very rare)
• Mental confusion (Rare)
• Agitation (Rare)
• Depression (Rare)
• Malaise (Rare)
• Abdominal pain (Common)
• Funddic gland polyp (Common)
• Nausea (Common)
• Constipation (Common)
• Vomiting (Common)
• Diarrhoea (Common)
• Flatulence (Common)
• Microscopic colitis Wrist fracture (Uncommon)
• Spinal fracture (Uncommon)
• Hip fracture (Uncommon)
• Muscle weakness (Very rare)
• Joint pain (Rare)
• Muscle pain (Rare)
• Rhabdomyolysis Headache (Common)
• Somnolence (Uncommon)
• Paraesthesia (Uncommon)
• Encephalopathy (Very rare)
• Bronchospasm (Rare)
• Interstitial nephropathy (Very rare)
• Renal impairment.

Allergy alert

Do not use if you are allergic to esomeprazole.

Esomeprazole may cause severe skin reactions.

Symptoms may include: skin reddening blisters rash If an allergic reaction occurs, stop use and seek medical help right away.

Directions adults 18 years of age and older this product is to be used once a day (every 24 hours), every day for 14 days may take to 4 days for full effect 14-Day Course of Treatment.

• swallow 1 tablet with a glass of water before eating in the morning.

• take every day for 14 days.

• do not take more than 1 tablet a day.

• swallow whole.

Do not crush or chew capsules.

• do not use for more than 14 days unless directed by your doctor Repeated 14-Day Courses (if needed).

• you may repeat a 14-day course every 4 months.

• do not take for more than 14 days or more often than every 4 months unless directed by a doctor children under 18 years of age: ask a doctor before use.

Heartburn in children may sometimes be caused by a serious condition.