GONAL-F
SERONO EUROPE
Identification
- Active ingredient (INN)
- FOLLITROPINE ALFA (HORMONE FOLLICULOSTIMULATE HUMAINE RECOMBINANTE (FSH RECOMBINANTE))
- Internal code
- 09 J 129
- Country of Origin
- United Kingdom
- Pharmaceutical form
- Powder + Solvent for SC Injectable Sol.
- Prescription List
- Highly Regulated (List I)
- Packaging
- b/1fl de pdre + une seringue pre remplie de 1ml solvant (eau preparation injectable)
DAWA Clinical Workbench v2.0
Information may not be accurate. Always consult a physician, pharmacist, or specialist before acting on any data shown here.
Associated Conditions
Lactation History of thromboembolic accident History of porphyry Hepatic impairment Renal impairment Tubary pathology, history Porphyry Porphyria, family history Subject at risk of thromboembolic accident Low weight Subject under 18 Ovarian hyperstimulation syndrome Ovarian hyperstimulation syndrome, history Polycystic ovary syndrome.
Mechanism of Action
Follitropin alfa
Mechanism of action Follitropin alfa (FSH) is a sexual and modulatory hormone of genital function, gonadotrophins.
In women, the most important effect of parenteral administration of FSH is the development of mature De Graaf follicles.
In anovulatory patients, the goal of treatment with GONAL-f is to develop a single mature De Graaf follicle from which the oocyte will be released after administration of hCG.
Adverse Effects
- Acne (Common)
- Gynecomastia (Common)
- Ovarian Kyste (Very common)
- Ovarian hyperstimulation syndrome (Common)
- Complication of ovarian hyperstimulation syndrome (Rare)
- Hypersensitivity (Very rare)
- Anaphylactic shock Anaphylactic reaction Injection site reaction (Very common)
- Injection site edema
- Erythema at the injection site Pain at injection site Hematoma at the injection site
- Irritation at the injection site Weight (increase) (Common)
- Varicole (Common)
- Thromboembolic accident (Very rare)
- Abdominal distension (Common)
- Abdominal pain (Common)
- Diarrhoea (Common)
- Nausea (Common)
- Digestive disorder (Common)
- Vomiting (Common)
- Headache (Very common)
- Asthma exacerbation (Very rare)
- Asthma (aggravation) (Very rare).